A hybrid model to test mechanical cues driving cell migration in angiogenesis

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• Anglique, S (CNRS (Centre National de la Recherche Scientifique))
• Tuesday 17 November 2015, 11:00-12:30
• Seminar Room 2, Newton Institute Gatehouse.

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Coupling Geometric PDEs with Physics for Cell Morphology, Motility and Pattern Formation

Many studies are stressing the crucial importance of the mechanical component in angiogenesis, but still, very few models really integrate mechanics. We propose to investigate the importance of mechanical cues for cell migration in this context with a new hybrid continuous-discrete model that describes the individual migration of contracting cells on an elastic matrix of fibres. The matrix is described as a continuum whereas the cells are described as discrete elements.

This talk is part of the Isaac Newton Institute Seminar Series series.

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