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Regulation of topographic order in the developing nervous system through dynamic cell adhesion

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If you have a question about this talk, please contact Catherine Pearson .

A major mode of organisation of neurons in vertebrate brains juxtaposes functionally related neurons into three dimensional clusters known as neuronal nuclei. Relatively little is known about how these clusters form during embryo development. During my talk, I shall discuss evidence that the combinatorial expression of multiple members of the cadherin family of cell adhesion molecules drives specificity of formation of neuronal nuclei. I shall illustrate this using three types of neuronal nuclei, spinal and cranial motor neurons and the brainstem neurons that birds use to calculate the location of a sound source in the horizontal plane.

This talk is part of the Institute for Energy and Environmental Flows (IEEF) series.

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Sanger Seminar Room, MRC LMB Alice Fisher Lecture Theatre, Addenbrooke's Site University of Cambridge Biomedical Campus (Addenbrooke’s Hospital Site) Clinical School Building SEMINAR ROOM 3

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