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Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
Thursday 12 October 2017, 13:00-14:00
Biomolecular condensates and their implications for neurodegenerative disease
- 👤 Speaker: Tony Hyman, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
- 📅 Date & Time: Thursday 12 October 2017, 13:00 - 14:00
- 📍 Venue: CRUK CI Lecture Theatre
Abstract
Cells organize many of their biochemical reactions by formation and dissolution of non-membrane-bound compartments. Recent experiments show that a common mechanism for such biochemical organization is phase separation of unstructured proteins to form liquid-like compartments. These liquid-like compartments can be described by principles elucidated from condensed-matter physics and are therefore termed biomolecular condensates. I will discuss the relationship between the formation of liquid like compartments, and the onset of aggregated-protein pathology that is commonly observed in neurodegenerative diseases.
Series This talk is part of the Cancer Research UK Cambridge Institute (CRUK CI) Seminars in Cancer series.
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