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Spreading the word about infectious protein misfolding

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Infectious diseases are traditionally thought to spread by living microorganisms, such as bacteria, viruses and fungi. Although proteins themselves are fundamentally not living, some are capable of spreading disease in an infectious manner through propagative misfolding. This disease principle underlies many neurological conditions, such as prion diseases, although not all are truly infectious. In this talk I will describe how proteins alone can act as infectious agents through misfolding, and how this phenomenon may be in fact be common to many neurodegenerative disorders, including Motor Neuron Disease.

This talk is part of the Pembroke Papers series.

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