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How the breakdown of Meckel’s cartilage offers clues to mammalian evolution

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If you have a question about this talk, please contact Olivia Tidswell .

The integration of the ancestral cranial mandibular joint into the middle ear and the parallel emergence of a novel jaw joint are two defining features of mammals. The separation of the middle ear ossicles from the mandible by the breakdown of Meckel’s cartilage is a key change during this evolution. By taking a comparative developmental biology approach, we have uncovered a number of cellular and molecular processes responsible for the unique mammalian anatomy. In doing so we aim to shed light onto the processes underlying the morphological changes observed in the fossil record.

This talk is part of the Evolution and Development Seminar Series series.

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