Molecular dissection approaches to study diseased tissues

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• Dr Walker Jackson, German Center for Neurodegenerative Diseases (DZNE)
• Wednesday 03 May 2017, 16:00-17:00
• Lecture Theatre 2, Department of Veterinary Medicine.

If you have a question about this talk, please contact Fiona Roby.

Neurodegenerative diseases (NDs) mercilessly transform a healthy adult brain into a progressively dysfunctional state. Differences in clinical manifestations (cognitive dysfunction in Alzheimer’s disease versus motor dysfunction in Parkinson’s disease) are the result of damage to specific brain cell types in specific brain regions. Effective therapies for NDs are currently very limited, partly due to the fact that most therapeutic discovery screens have relied on limited types of cultured cells that incompletely mimic the relevant disease state in the brain. In recent years we have employed and refined techniques that enable the identification of affected cell types and disease mechanisms in complex tissues. Although our work focuses on mouse models of brain diseases (prion diseases for example) the approaches we employ could also be adapted to other species and tissues.

This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Cambridge Immunology
• Cambridge Infectious Disease
• Cambridge Infectious Diseases
• Departmental Seminar Programme, Department of Veterinary Medicine
• Lecture Theatre 2, Department of Veterinary Medicine
• Vet School Seminars

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