Resilience vs Vulnerability to Compulsion: behavioral, neurochemical and psychopharmacological evidences in rats selected by Schedule-induced polidipsia

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• Dr Margarita Moreno, Tenured Lecturer, Psychology Department, University of Almería, Spain
• Wednesday 12 July 2017, 13:00-14:00
• Ground Floor Lecture Theatre, Department of Psychology, Downing Site, Cambridge.

If you have a question about this talk, please contact Lorraine Coulson.

Compulsive behaviour is present in different psychiatric disorders such as OCD , schizophrenia and drug abuse. In our laboratory we investigate a compulsive phenotype of rats, selected by Schedule-Induced Polydipsia (SIP).This procedure, characterized by the development of nonregulatory excessive drinking under intermittent food reinforcement schedules, has been previously proposed as a successful model for obsessive–compulsive disorder (OCD), schizophrenia, and alcohol abuse. The lecture review our main findings in High compulsive drinker rats (HD) versus Low drinker rats (LD) on SIP ; through the assessment of individual differences in other behaviours related to compulsive spectrum disorders, psychopharmacology, brain neurochemistry and receptors. These studies contribute to elucidate the mechanisms underlying the vulnerability to compulsion , improving our knowledge of possible new markers and insights for potential treatments on compulsive behaviours in neuropsychiatric populations.

This talk is part of the Behavioural and Clinical Neuroscience Seminars series.

This talk is included in these lists:

• BCNI seminars
• Behavioural and Clinical Neuroscience Seminars
• Cambridge talks
• Department of Psychiatry talks stream
• Ground Floor Lecture Theatre, Department of Psychology, Downing Site, Cambridge
• Psychology talks and events
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