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Form, flow, deformation, and transport in the embryonic lung

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GFSW01 - Form and deformation in solid and fluid mechanics

The mammalian airway branches prenatally in a limited number of stereotyped modes. It is well established that various experimental interventions can change the nature of the branching. We have developed several  hypotheses for the mechanisms governing this mode selection, including the potential roles of geometry, mechanics, and transport, and interactions between the three. We developed a suite of models testing the implications of these hypotheses. Our models rule out some hypotheses and support others. 

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