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Sequencing hundreds of humans - how to collect the data efficiently and make sense of it

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If you have a question about this talk, please contact David MacKay .

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New technologies are dropping the cost of DNA sequencing by two orders of magnitude. We can therefore consider sequencing hundreds of humans to gain a comprehensive picture of human genetic variation. However, the way our genomes are related is via the genomes of our remote ancestors, which are inaccessible. Just now my plans for this talk are to try to explain the nature of this hidden variable problem, why inference on it is hard, and how some of the current approximations work. I believe there is scope for improvement.

This talk is part of the Machine Learning and Inference (One day meeting) series.

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