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Plant intracellular immune receptors; diversity, deployment and dissection

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Diverse microbes cause plant disease, and plants have evolved a robust innate immune system that recognizes pathogen molecules and then activates defense. Immunity involves both cell surface receptors (usually transmembrane protein kinases) also intracellular NLR immune receptors, encoded byResistance® genes. Plant NLRs are modular proteins and usually carry an N-terminal signaling domain, followed by a nucleotide-binding domain and C-terminal LRRs. NLRs either directly recognize pathogen effector molecules, or recognize the effects of these effectors on host proteins. Plants show extensive within- and between-species diversity in their NLR -encoding repertoires, which we investigate using sequence capture methods, and polymorphism in population NLR repertoires is important for their efficacy.

This talk is part of the Plant Sciences Departmental Seminars series.

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