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SUMMARY:Imaging the Molecular Pathology of Alzheimer’s disease - William
  Jagust\, UC Berkeley School of Public Health
DTSTART:20180504T130000Z
DTEND:20180504T140000Z
UID:TALK105400@talks.cam.ac.uk
CONTACT:Rachel Furner
DESCRIPTION:Recent advances in molecular imaging using positron emission t
 omography have permitted the 4-dimensional mapping of Alzheimer’s diseas
 e related pathology. The two aggregated proteins\, beta-amyloid and tau\, 
 can now be visualized\, along with the presumptive consequences of their d
 eposition - brain degeneration and cognitive decline. This talk will revie
 w both cross sectional and longitudinal data concerning how tau and amyloi
 d interact\, and how they are related to neurodegeneration and cognition. 
 The framework for discussion is a sequential model of biomarker changes. T
 he question of whether and how well the observed data fit this model will 
 be discussed.
LOCATION:MR11\, Centre for Mathematical Sciences
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