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SUMMARY:The Mechanics of DNA and its Assemblies: From Twist-Bend Coupling 
 to Cholesteric Liquid Crystals - Professor Jonathan Doye\, University of O
 xford
DTSTART:20181003T131500Z
DTEND:20181003T141500Z
UID:TALK108235@talks.cam.ac.uk
CONTACT:Lisa Masters
DESCRIPTION:In this talk\, I will provide an overview of the insights that
  have been obtained into the mechanical properties of DNA and its assembli
 es using oxDNA\, a coarse-grained nucleotide-level DNA model developed in 
 the Doye and Louis groups. Topics will include twist-bend coupling\, DNA o
 verstretching\, extreme bending\, polymerase binding\, plectoneme formatio
 n (including in the presence of DNA damage)\, solenoid formation\, the pro
 perties of extremely underwound (L-DNA) and overwound (P-DNA)\, the elasti
 c properties of DNA origamis\, the unravelling of DNA origamis under tensi
 on\, and the cholesteric liquid-crystalline properties of both duplex DNA 
 and twisted rod-like DNA origamis.
LOCATION:Department of Chemistry\, Cambridge\, Unilever lecture theatre
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