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SUMMARY:Reprogramming roots for fungal symbiosis - Leonie Luginbuehl\, Hib
 berd group
DTSTART:20181018T120000Z
DTEND:20181018T123000Z
UID:TALK112135@talks.cam.ac.uk
CONTACT:Ronelle Roth
DESCRIPTION:A major limitation to plant growth is restricted access to nut
 rients in the soil. To improve nutrient acquisition\, the majority of land
  plants enter a beneficial symbiosis with arbuscular mycorrhizal (AM) fung
 i. In return for mineral nutrients\, plants deliver fixed carbon to the ob
 ligate biotrophic fungus. This nutrient exchange takes place through highl
 y branched hyphal structures called arbuscules that form in the inner cort
 ical cells of the root. Accommodating fungal hyphae in roots requires exte
 nsive transcriptional reprogramming of host cells. Several GRAS-domain pro
 teins\, including NSP1 (NODULATION SIGNALLING PATHWAY 1) and RAM1 (REQUIRE
 D FOR ARBUSCULAR MYCORRHIZATION 1)\, have emerged as important transcripti
 onal regulators during mycorrhizal colonization\, however\, little is know
 n about the target genes and biological processes that are regulated by th
 ese transcription factors. We investigated the functions of NSP1 and RAM1 
 during AM development by detailed phenotypic and transcriptional analyses 
 of the corresponding loss‐of‐function mutants. We found that NSP1 is r
 equired for the expression of a large number of genes involved in strigola
 ctone biosynthesis at the pre‐contact stage of AM development. Unlike NS
 P1\, RAM1 plays a critical role in the transcriptional control at later st
 ages of AM symbiosis\, regulating the expression of several genes involved
  in a lipid biosynthesis and export pathway that supplies fatty acids to a
 rbuscular mycorrhizal fungi\, which are fatty acid auxotrophs.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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