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SUMMARY:Designing Dementia Trials Embedded Within a Cohort - Mary Fortune 
 (University of Cambridge)
DTSTART:20190224T103000Z
DTEND:20190224T110500Z
UID:TALK120772@talks.cam.ac.uk
CONTACT:73969
DESCRIPTION:Clinical trial recruitment sounds like it should be a job for 
 the medics\, not the mathematicians. But what if you already have access t
 o decades of data about your prospective participants\, and want to select
  those who you wish to invite to take part based on mathematical predicati
 on of how their disease will progress? In many dementia trials\, the focus
  is upon patients who are asymptomatic or at an early stage in the disease
 . We would like to choose trial participants who are likely to benefit fro
 m the treatment. However\, if our recruitment is too selective\, we may no
 t be able to say anything about the effect of the treatment in the whole p
 opulation. Any strategy needs to balance the pay-off between these two fac
 tors
LOCATION:Winstanley Lecture Theatre\, Trinity College
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