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SUMMARY:Rare events and the flipping of genetic switches - Dr Rosalind All
 en\, School of Physics\, University of Edinburgh
DTSTART:20081114T141500Z
DTEND:20081114T151500Z
UID:TALK13725@talks.cam.ac.uk
CONTACT:Kevin Chalut
DESCRIPTION:Processes that happen randomly and infrequently\, but with dra
 matic consequences\, are notoriously difficult to simulate. I will discuss
  a method that we have developed\, known as Forward Flux Sampling\, for\ns
 imulating these rare events in equilibrium or nonequilibrium systems. We h
 ave applied this method to the flipping of the genetic switch that control
 s the developmental transition from lysogeny to lysis in\nbacteriophage la
 mbda. Our results lead to some general conclusions about stochastic modell
 ing of gene regulatory networks.\n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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