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SUMMARY:A singular view of DNA transactions - Dr Gijs Wuite\, Department o
 f Physics and Astronomy\, VU University Amsterdam\, Netherlands
DTSTART:20081128T141500Z
DTEND:20081128T151500Z
UID:TALK13726@talks.cam.ac.uk
CONTACT:Jurij Kotar
DESCRIPTION:The genetic information of an organism is encoded in the base 
 pair sequence of its DNA. Many specialized proteins are involved in organi
 zing\, preserving and processing the vast amounts of information on the DN
 A. In order to do this swiftly and correctly these proteins have to move q
 uickly and accurately along and/or around the DNA constantly rearranging i
 t. In order to elucidate these processes we perform single-molecule experi
 ments on model systems such as restriction enzymes\, bacterial gene regula
 tors and repair proteins.\n\nThe data we use to extract forces\, energies 
 and mechanochemistry driving these dynamic transactions. The results obtai
 ned from these model systems are then generalized and thought to be applic
 able to many DNA-protein interactions.\n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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