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SUMMARY:The frontline of vaccine development - Professor Margaret Stanley\
 , Professor Jonathan Heeley\, Professor Derek Smith
DTSTART:20200129T193000Z
DTEND:20200129T220000Z
UID:TALK139072@talks.cam.ac.uk
CONTACT:87532
DESCRIPTION:Vaccines have saved millions of lives worldwide\, and are a ke
 y global health intervention. In this talk\, we are thrilled to have three
  eminent professors speaking\, all experts working to develop new vaccines
  for diseases such as influenza\, HPV and Ebola. Each speaker will give an
  insight into their work\, before coming together as a panel to discuss th
 e role of vaccination in the fight against infectious disease. \n\nOur spe
 akers: \n*Professor Margaret Stanley*\nEvery 2 minutes somewhere in the wo
 rld a woman dies of cervical cancer - cancer caused by infection with the 
 human papillomavirus (HPV) and is a preventable disease. Currently\, there
  are 3 prophylactic virus-like particle (VLP) vaccines being developed\, u
 sing sophisticated recombinant molecular techniques and protein expression
 . In this talk\, Professor Margaret Stanley shares her work on the human p
 apillomavirus and the current vaccination schemes for HPV. She is currentl
 y an Emeritus Professor of Epithelial Biology in the Department of Patholo
 gy\, Cambridge. She also serves as the President of the International Papi
 llomavirus Society (IPVS) and is very active in advocating for HPV vaccina
 tion. She sits on the Working Group for HPV vaccines advising the WHO Stra
 tegic Advisory group of Experts (SAGE). In 2010\, Professor Stanley was gi
 ven the Lifetime Achievement Award by the American Society for Colposcopy 
 and Cervical Pathology (ASCCP) for her contributions to cervical cancer an
 d cervical pre-cancers research.\n\n\n*Professor Derek Smith*\nIn his talk
 \, Professor Derek Smith will discuss his work on studying the evolution o
 f the influenza virus and other rapidly evolving pathogens. Professor Smit
 h is the director of the Centre for Pathogen Evolution here in Cambridge a
 s well as a research scientist in the Department of Virology at Erasmus Me
 dical Center Rotterdam. His work has proved salient for the development of
  vaccines for modern day epidemics. His experimental and mathematical work
  is currently being used to predict the evolution of the influenza virus\,
  and he works with the WHO to select the composition of the influenza vacc
 ine (each year).\n\n\n*Professor Jonathan Heeney*\nIn his talk\, Professor
  Jonathan Heeney will discuss a trivalent haemorrhagic fever vaccine again
 st Lassa Fever\, Marbug\, Ebola and related Filoviruses using novel vaccin
 e technology. These haemorrhagic fever viruses are among the most highly c
 ontagious viruses in Africa and are listed as top-10 priority diseases by 
 the World Health Organisation. They occur in overlapping regions of sub-Sa
 haran Africa and a single vaccine to prevent outbreaks of haemorrhagic fev
 er caused by these arenaviruses and filoviruses would be of great public a
 nd global health benefit. \nJonathan Heeney is Head of The Laboratory of V
 iral Zoonotics. His research focuses on cross species transmissions of vir
 uses\, and the co-evolution of viruses and their hosts including the evolu
 tion of immune mechanisms of disease protection in naturally infected but 
 disease resistant species. Not only has this interest led to the discovery
  of a number of new viruses\, but also genetic comparison of host and vira
 l sequences from the same individual.\nCurrently his laboratory applies th
 ese molecular technologies to gain an understanding of successful host imm
 une responses to RNA viruses. Translationally this information is utilized
  for the rational design of novel vaccines for the prevention of diseases 
 caused by notoriously complex viral pathogens. 
LOCATION:Old Divinity School Main Lecture Theatre\, St John’s College
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