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SUMMARY:Biomolecular adsorption at a silicon/water interface driven by wat
 er-structure effects - Daniel J. Cole\, Theory of Condensed Matter (TCM) G
 roup\, Cavendish Laboratory
DTSTART:20090122T160000Z
DTEND:20090122T170000Z
UID:TALK15204@talks.cam.ac.uk
CONTACT:Stephen Walley
DESCRIPTION:The issue of protein adsorption onto solid surfaces in a wet e
 nvironment is of great importance for the design and functionalisation of 
 materials in the context of biomedical implants. We investigate the adsorp
 tion of the extracellular matrix protein\, collagen\, on hydrophobic and h
 ydrophilic silicon surfaces using all-atom molecular dynamics. Adhesion is
  determined by a mutual fit between the hydrophilic/hydrophobic pattern wi
 thin the protein and the layered water structure at the solid/liquid inter
 face\, providing an additional driving force to the hydrophobic effect.
LOCATION:Mott Seminar Room\, Cavendish Laboratory\, Department of Physics
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