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SUMMARY:Multitrophic metabolism underlies plant-nematode interactions - Fr
 ank C. Schroeder\, Cornell University
DTSTART:20210121T130000Z
DTEND:20210121T140000Z
UID:TALK154642@talks.cam.ac.uk
CONTACT:85030
DESCRIPTION:Bacteria\, fungi\, and nematodes in the rhizosphere have profo
 und impacts on all aspects of plant biology\, and small-molecule signaling
  is presumed to play a central role in mediating these interactions. We fo
 und that ascaroside pheromones secreted by plant-parasitic nematodes are m
 etabolized by plants and associated microorganisms in a manner that can st
 arkly alter the chemical message encoded by these pheromones. For example\
 , comparative metabolomics of monocots and dicots revealed that nematode-d
 erived ascarosides that are attractive to other nematodes are converted in
 to derivatives that confer repellency. An Arabidopsis mutant defective in 
 two peroxisomal acyl-CoA oxidases does not metabolize ascr#18 and does not
  repel nematodes\, indicating that plants\, like nematodes\, employ conser
 ved peroxisomal β-oxidation to edit ascarosides and change their message.
  These findings suggest that plant-editing of nematode pheromones may repr
 esent a broadly conserved defense mechanism that acts in parallel to conve
 ntional pattern-triggered immunity. Moreover\, we found that\, in addition
  to triggering defense responses\, ascarosides can directly modulate plant
  growth and development.  Fungi and some bacteria can also metabolize nema
 tode-derived ascarosides\, demonstrating that plants and microorganisms ar
 e part of a biosynthetic network that can actively modulate and interfere 
 with chemical signaling across phyla.\n\nContact reception@plantsci.cam.ac
 .uk for a Zoom link prior to a talk if you are not on our mailing list. Du
 e to having to go onine\, we are restricting the talks to University of Ca
 mbridge and alumni to keep them as informal as possible.
LOCATION:Online
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