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SUMMARY:To COVID-19 Detection: How physics can be used to create novel tes
 ts for viruses - Professor Ulrich Keyser 
DTSTART:20211116T180000Z
DTEND:20211116T193000Z
UID:TALK165961@talks.cam.ac.uk
CONTACT:92260
DESCRIPTION:DNA nanotechnology is transformative for experiments that requ
 ire molecular control over the shape of nanometer-sized objects. In combin
 ation with nanopores\, DNA self-assembly allows for novel experiments that
  reveal the physics of ions\, and polymers on the single-molecule level.\n
 \nNanopore sensing\, best known for DNA sequencing\, translates the three-
 dimensional structure of molecules into ionic current signals. Designed DN
 A molecules enable multiplexed protein sensing with an all-electrical appr
 oach. Here\, Professor Ulrich Keyser will discuss his group’s recent dev
 elopments to detect and localize structures as accurately as possible alon
 g DNA molecules approaching super-resolution microscopy. The localization 
 is enabled by a quantitative understanding of polymer dynamics in our glas
 s nanopores which enables it to extract position information to a few ten 
 base pairs. In the last part of the talk\, he will explain how we used our
  knowledge on single-molecules and nanopores to crate a novel test for vir
 uses and their variants that may play a role in (the prevention of) future
  pandemics.
LOCATION:Wolfson Lecture Theatre\,  Department of Chemistry\, Lensfield Ro
 ad
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