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SUMMARY:HUNTING THE ANTISOCIAL CANCER CELL - Prof. Ron Laskey\, MRC Cancer
  Cell Unit\, Cambridge
DTSTART:20091001T180000Z
DTEND:20091001T190000Z
UID:TALK16626@talks.cam.ac.uk
CONTACT:John Wilkins
DESCRIPTION:One of the most effective ways of improving cancer treatments 
 is to improve early diagnosis\, so that cancers are detected before they s
 pread. Proteins that regulate DNA replication provide a new approach to th
 is problem. Replicating the human genome during each cell cycle is an enor
 mous logistical challenge. 105 replication initiation events must be co-or
 dinated so that all of the DNA is replicated once\, exactly once and only 
 once. How does the cell keep track of which regions it has already replica
 ted?  The answer lies in a ratchet-like system of “replication licensing
 ”. Proteins that make up the license are remarkably powerful markers for
  improving cancer screening and diagnosis. \n\nProf Laskey started his car
 eer at Oxford\, followed by post-doctoral posts on the scientific staff of
  Imperial Cancer Research Fund and the MRC Laboratory of Molecular Biology
  in Cambridge. In 1983 he moved to the Charles Darwin Chair in the Univers
 ity of Cambridge\, first in the Department of Zoology\, then in the Wellco
 me CRC Institute and now as Director of the MRC Cancer Cell Unit in the Hu
 tchison/MRC Research Centre. \n\nHe is a Fellow of Darwin College and a Fe
 llow of the Royal Society. His work has been recognised by awards from sev
 eral countries\, including the Louis Jeantet Prize for Medicine. He has or
 ganised and edited two series of Darwin College Lectures. On a lighter not
 e\, he has written and recorded two albums called Songs for Cynical Scient
 ists and More Songs for Cynical Scientists. We hope that we can persuade h
 im to sing for us after the lecture.\n\nSuitable for A-level students.\n\n
LOCATION:Department of Chemistry\, Lensfield Road\, Cambridge
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