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SUMMARY:LMB Seminar:  Engineering Organoid Development - Professor Matthia
 s Lutolf\, Roche Institute for Translational Bioengineering\, Basel\, Swit
 zerland and Laboratory of Stem Cell Bioengineering\, EPFL\, Switzerland
DTSTART:20220419T100000Z
DTEND:20220419T110000Z
UID:TALK172016@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Organoids form through poorly understood morphogenetic process
 es in which initially homogeneous ensembles of stem cells spontaneously se
 lf-organize in suspension or within permissive three-dimensional extracell
 ular matrices. Yet\, the absence of virtually any predefined patterning in
 fluences such as morphogen gradients or mechanical cues results in an exte
 nsive heterogeneity. Moreover\, the current mismatch in shape\, size and l
 ifespan between native organs and their in vitro counterparts hinders thei
 r even wider applicability. In this talk I will discuss some of our ongoin
 g efforts in developing next-generation organoids that are assembled by gu
 iding cell-intrinsic self-patterning through engineered stem cell microenv
 ironments.\n
LOCATION:Zoom link: https://mrc-lmb-cam-ac-uk.zoom.us/j/97051627883?pwd=cU
 h3ZDZkT3I2bHdxVXo0TytZSEJkdz09
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