BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Microbial spatial self-organization and the spread of plasmid-enco
 ded functional novelty - David Johnson (None / Other)
DTSTART:20221013T100000Z
DTEND:20221013T103500Z
UID:TALK179381@talks.cam.ac.uk
DESCRIPTION:Spatial self-organization\, where different cell-types arrange
  themselves non-randomly across space\, is a hallmark of surface-associate
 d microbial communities. Metabolic interactions are an important determina
 nt of the spatial self-organization process\, where they direct the spatia
 l positionings of individuals. We hypothesized here that these metabolic i
 nteraction-induced spatial positionings control the spread of plasmid-enco
 ded functional novelty. Using a combination of experiments and individual-
 based computational simulations\, I will illustrate how metabolic interact
 ion-induced spatial positionings determine both the extent of plasmid tran
 sfer (HGT) and the proliferation of new cell-types after plasmid acquisiti
 on (VGT). I will also argue how these outcomes are important for predictin
 g and controlling the fate of plasmid-encoded traits within surface-associ
 ated microbial communities. Finally\, I will highlight new research gaps a
 nd propose future areas for scientific inquiry.
LOCATION:Seminar Room 1\, Newton Institute
END:VEVENT
END:VCALENDAR