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SUMMARY:Exploring the origin of multicellularity in real time: what we've 
 learned from 5\,000 generations of laboratory evolution - William Ratcliff
 \, Georgia Tech
DTSTART:20221008T120000Z
DTEND:20221008T130000Z
UID:TALK183917@talks.cam.ac.uk
CONTACT:Dr Emily Mitchell
DESCRIPTION:The origin of multicellularity was one of the most significant
  innovations in the history of life. Our understanding of the evolutionary
  processes underlying this transition remains limited\, however\, mainly b
 ecause extant multicellular lineages are ancient and most transitional for
 ms have been lost to extinction. We bridge this knowledge gap by evolving 
 novel multicellularity in the lab\, using the 'snowflake yeast' model syst
 em. In this talk\, I'll focus on our ongoing Multicellular Long-Term Evolu
 tion Experiment (MuLTEE)\, in which we've put snowflake yeast through ~5\,
 000 generations of selection for larger size and faster growth. We will ex
 amine key steps in the evolution of multicellularity\, namely how multicel
 lular traits arise and become heritable\, how simple multicellular bodies 
 evolve to become radically stronger and tougher\, and how cells divide lab
 or through differentiation. Overall\, our approach allows us to examine ho
 w simple groups of cells can evolve to become increasingly integrated and 
 organismal\, providing novel insight into this major evolutionary transiti
 on. \n\n
LOCATION:Venue to be confirmed
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