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SUMMARY:Homeostatic Modulation of Neural Function: From Phenomenology to M
 olecular Design - Professor Graeme Davis\, University of California\, San-
 Francisco\, USA.
DTSTART:20090617T130000Z
DTEND:20090617T140000Z
UID:TALK18819@talks.cam.ac.uk
CONTACT:Hannah Critchlow
DESCRIPTION:Research Interests: There are two major research objectives in
  the laboratory. We would like to understand at a molecular level how indi
 vidual cells\, neurons or muscle\, achieve stable levels of activity durin
 g development and throughout life. We hypothesize that each cell in the ne
 rvous system is endowed with potent homeostatic mechanisms that enable cel
 lular activity levels to be regulated. Understanding these homeostatic mec
 hanisms may have far-reaching implications for understanding and treating 
 neural disease.\n\nThe second major objective of the laboratory is to unde
 rstand the cellular mechanisms that control synaptic growth in the nervous
  system. How are the stereotyped sizes and morphologies of synapses determ
 ined during development? What are the cellular and molecular mechanisms th
 at modulate the addition or elimination of transmitter release machinery w
 ithin a synapse during development? Understanding how neuronal and synapti
 c growth is normally controlled may provide the opportunity to manipulate 
 synaptic function for the treatment of neurodegenerative disease or injury
  to the nervous system.\n\n
LOCATION:Hodgkin-Huxley Room\, Department of Physiology\, Development and 
 Neuroscience\, Physiology Building\, Downing Site
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