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SUMMARY:Dynamic modelling of chorded mitral valve - Luo\, X (Glasgow)
DTSTART:20090722T133000Z
DTEND:20090722T134500Z
UID:TALK19160@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:The dynamic behaviour of a novel chorded mitral prosthesis is 
 studied using an immersed boundary model. To investigate the mechanical be
 haviour of the mitral design under physiological flow conditions without h
 aving to model the left ventricle\, we make use of in vivo magnetic resona
 nce images of the left ventricle. The relative motion of the mitral annulu
 s and motion of the ventricle determined from these MRI images is then use
 d as a prescribed boundary condition for the chorded mitral valve in a dyn
 amic cycle. This model allows us to investigate the influences of the flow
  vortex generated by the ventricle motion on the valve dynamics\, as well 
 as the effect of the motion of the chordae attachment points. Results are 
 compared with two other cases: (i) a ventricle model with no prescribed mo
 tion of the chordae attachment points\, (ii) a tube model in which the ven
 tricle is replaced by a tube\, although the motion of the chordae is incor
 porated. It is found that the vortex flow helps to reduce the cross valve 
 pressure gradient\; however\, it can significantly increase the chordae an
 d the valve stretch in the commissural region and make the flow field stro
 ngly asymmetric. Surprisingly\, we observe that the presence of the flow v
 ortex does not necessarily aid the valve closure. 
LOCATION:Seminar Room 1\, Newton Institute
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