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SUMMARY:Measurement uncertainties in neutron and gamma-ray imaging for pro
 ton range monitoring - Lena Setterdahl (Western Norway University of Appli
 ed Sciences)
DTSTART:20230517T083000Z
DTEND:20230517T090000Z
UID:TALK198616@talks.cam.ac.uk
DESCRIPTION:\nProton therapy is a highly effective method for treating tum
 ors. However\, its potential is not fully realized due to proton beam rang
 e uncertainties caused by\, e.g.\, patient positioning and anatomical chan
 ges. The current solution is increased treatment margins (typically 3.5% o
 f the beam range) to fully cover the treatment volume but at a cost of als
 o irradiating surrounding healthy tissue.\nTo fully exploit the dosimetric
  benefits of proton therapy\, these treatment margins need to be reduced. 
 Recent pursuits have been made toward monitoring the proton beam range in 
 real-time to enable more accurate radiation dose delivery and reduction of
  treatment margins. This includes a novel approach proposed by the NOVO pr
 oject in which optically segmented plastic scintillator bars\, also referr
 ed to as a The NOVO Compact Detector Array (NOVCoDA)\, will be used to ima
 ge the production distribution of the prompt-gamma rays (PGs) and fast neu
 trons (FNs) produced in nuclear reactions inside the patient during treatm
 ent. The NOVCoDA imaging principle is based on triple and double scatterin
 g for PGs and FNs\, respectively\, and measuring the deposited energy and 
 scattering position for both particles and\, additionally\, time-of-flight
  for FNs to construct an image of their production distribution. Minimizin
 g the NOVCoDA's measurement uncertainties is essential to achieve precise 
 image reconstruction.\nIn this talk\, the nature and effect of these uncer
 tainties will be presented along with demonstrations (based on Geant4 simu
 lations) of their impact on image reconstruction using the geometrical ope
 ration known in the physics community as the simple back projection method
 . The image quality will be quantified by image resolution\, i.e. the full
  width at half maximum (FWHM) of the point spread function.\n
LOCATION:Seminar Room 1\, Newton Institute
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