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SUMMARY:Modeling and topological data analysis of pattern formation in fis
 h skin - Alexandria Volkening (Purdue University)
DTSTART:20230809T101500Z
DTEND:20230809T111500Z
UID:TALK201460@talks.cam.ac.uk
DESCRIPTION:Pattern formation is present at many scales in biology\, and h
 ere I will focus specifically on elucidating how brightly colored cells in
 teract to form skin patterns in zebrafish. Wild-type zebrafish are named f
 or their dark and light stripes\, but mutant zebrafish feature variable sk
 in patterns\, including spots and labyrinth curves. All of these patterns 
 form as the fish grow due to the interactions of tens of thousands of pigm
 ent cells\, making agent-based modeling a natural approach for describing 
 pattern formation. However\, agent-based models are stochastic and have ma
 ny parameters\, so comparing simulated patterns and fish images is often a
  qualitative process. Here I will show how to apply methods from topologic
 al data analysis to cell-based\, time-dynamic systems. In this talk\, I wi
 ll overview our models and present quantitative summaries of messy cell-ba
 sed patterns forming in time.
LOCATION:Seminar Room 1\, Newton Institute
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