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SUMMARY:LMB Seminar: From regeneration to homeostasis: tissue-scale decisi
 on making - Pros. Prisca Liberali
DTSTART:20240115T110000Z
DTEND:20240115T120000Z
UID:TALK202063@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Multicellular organisms are composed of cells and tissues with
  identical genomes but different properties and functions. They all develo
 p from one cell to form multicellular structures of astounding complexity.
  During development\, in a series of spatio-temporal coordinated steps\, c
 ells differentiate into different cell types and establish tissue-scale ar
 chitectures and functions. Throughout life\, continuous tissue renewal and
  regeneration is required for tissue homeostasis\, which also requires fin
 e-tuned spatio-temporal coordination of cells. I will discuss how cellular
  interactions generate the specific contexts and spatio-temporal coordinat
 ion underlying development and regeneration and how we specifically invest
 igate what are the molecular and physical mechanisms that allow a cell\, i
 n a tissue\, to sense its complex environment\, to take individual coordin
 ated decisions. Moreover\, I will discuss the molecular mechanisms of inte
 stinal organoid self-organization and the role of cell-to-cell variability
  in populations of differentiating cells during symmetry breaking.\n\nTwit
 ter/X Handle - @priscaliberali
LOCATION:In person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoo
 m\, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/97161414783?pwd=UEhEZUdDSVVL
 bDU0Q2lPdFhPQ3M2UT09
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