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SUMMARY:The genetic basis of a recent transition to live-bearing in marine
  snails - Sean Stankowski\; University of Sussex\, UK
DTSTART:20240220T160000Z
DTEND:20240220T170000Z
UID:TALK205630@talks.cam.ac.uk
CONTACT:Dr Joana Meier
DESCRIPTION:Key innovations are fundamental to biological diversification\
 , but their genetic basis is poorly understood. A recent transition from e
 gg-laying to live-bearing in marine snails (Littorina) provides the opport
 unity to study the genetic architecture of an innovation that has evolved 
 repeatedly across animals. Individuals do not cluster by reproductive mode
  in a genome-wide phylogeny\, but local genealogical analysis revealed num
 erous small genomic regions where all live-bearers carry the same core hap
 lotype. Candidate regions show evidence for live-bearer-specific positive 
 selection and are enriched for genes that are differentially expressed bet
 ween egg-laying and live-bearing reproductive systems. Ages of selective s
 weeps suggest live-bearer-specific alleles accumulated over ~200k generati
 ons. Our results suggest that novel functions evolve through the recruitme
 nt of many alleles\, rather than in a single evolutionary step.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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