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SUMMARY:Selecting chemical processes and sequences at the molecular origin
 s of life - Ivar Svalheim Haugerud (Universität Augsburg)
DTSTART:20231215T143000Z
DTEND:20231215T150000Z
UID:TALK209419@talks.cam.ac.uk
DESCRIPTION:\nPhase separation and non-equilibrium conditions such as wet-
 dry cycles were ubiquitous at the molecular origin of Life. How phase sepa
 ration affects chemical processes\, such as the formation of specific sequ
 ences such as DNA or RNA\, that are crucial for the RNA world hypothesis\,
  remains elusive. Here\, we propose a theory for the kinetics of chemical 
 processes in a non-dilute\, phase-separating mixture subject to wet-dry cy
 cles. We show that the cycle frequency strongly affects the chemical turno
 ver. A resonance behavior exists in the cycle frequency where the turnover
  is maximal. We also use our theory to study the formation of sequences. W
 hen sequences phase separate\, the sequence distribution is strongly alter
 ed. Thus\, specific sequences get selected when subject to wet-dry cycles\
 , suggesting a potential mechanism for chemical evolution in prebiotic sou
 ps on early Earth.\n&nbsp\;\nCo authors: Pranay Jaiswal\, Giacomo Bartoluc
 ci\, Christoph A. Weber.\n
LOCATION:Seminar Room 2\, Newton Institute
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