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SUMMARY:Cell size - A new hallmark of aging? - Jette Lengefeld\, Universit
 y of Helsinki and Karolinska Institute
DTSTART:20240226T123000Z
DTEND:20240226T133000Z
UID:TALK209953@talks.cam.ac.uk
CONTACT:Kate Davenport
DESCRIPTION:Years of important research has revealed that cells heavily in
 vest in regulating their size. Nevertheless\, it has remained unclear why 
 accurate size control is so important. \nOur recent study using hematopoie
 tic stem cells (HSCs) in vivo indicates that cellular enlargement is causa
 lly associated with aging. I present an overview of these findings and the
 ir implications. Furthermore\, I present a broad literature analysis to ev
 aluate the potential of cellular enlargement as a new aging hallmark and I
  highlight interesting work showing a correlation between cell size and ag
 e-related diseases. Taken together\, I will present mounting evidence link
 ing cellular enlargement to aging and age-related diseases. \n
LOCATION:CRUK CI Lecture Theatre
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