BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Genetic Testing in the Clinic for the APOE gene: A Cautionary Tale
  - Dr Margaret Lock. See: www.mcgill.ca/ssom/facultyinfo/lock/
DTSTART:20091125T130000Z
DTEND:20091125T140000Z
UID:TALK21206@talks.cam.ac.uk
CONTACT:16168
DESCRIPTION:It is commonly assumed that costs of individual genotyping wil
 l steadily decrease over the next few years\, leading certain researchers 
 and policy makers to argue that genetic testing for certain complex diseas
 es should be routinized to improve clinical care. In this presentation I w
 ill first indicate some of the difficulties involved in conveying the comp
 lex\, unfolding knowledge about AD genetics to patients\, their families\,
  and the public at large. Findings will then be presented from interviews 
 with individuals\, themselves unaffected by AD\, but whose families have o
 ne or more member diagnosed with AD\, and who participated in the Risk Eva
 luation and Education for Alzheimer's Disease study\, an RCT carried out a
 t four sites in the US in which subjects were genotyped and informed about
  their APOE status. One year later\, less than one quarter of the intervie
 wees recall their genotype or risk estimates correctly and family history 
 is regarded by virtually all as a better indicator of future disease than 
 is genetic testing. The questionable worth of individualized risk estimate
 s will also be discussed.\n
LOCATION:Institute of Public Health\, University Forvie Site\, Addenbrooke
 's site\, small seminar room
END:VEVENT
END:VCALENDAR