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SUMMARY:Association mapping and prediction of complex structured phenotype
 s - Oliver Stegle (Max Planck Institutes\, Tübingen)
DTSTART:20091030T140000Z
DTEND:20091030T150000Z
UID:TALK21279@talks.cam.ac.uk
CONTACT:Emli-Mari Nel
DESCRIPTION:The goal of genetic association studies is to relate polymorph
 ic genetic loci with quantitative traits that capture phenotypic variation
 .This task is well studied for a univariate or multiple independent trait 
 variables. However\, modern high-dimensional phentoypes often exhibit stru
 cture\, which needs to be accounted for. In this talk I will discuss learn
 ing techniques that explicitly address this structure and allow for improv
 ed mapping and prediction of such phenotypic traits. \n\nhttp://www.kyb.mp
 g.de/de/~stegle\n\nThe discussion includes methods to account for confound
 ing factors and phenotypes that are recorded as a time series. Application
 s include the prediction of the depression state of patients over the cour
 se of a treatment.
LOCATION:TCM Seminar Room\, Cavendish Laboratory\, Department of Physics
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