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SUMMARY:Embryo-scale reverse genetics at single cell resolution reveals li
 neage-specific modules underlying cranial development - Professor Lauren S
 aunders from Centre for Organismal Studies\, Heidelberg University   
DTSTART:20250213T140000Z
DTEND:20250213T150000Z
UID:TALK219436@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:The Saunders lab is interested in understanding the interplay 
 between a cell's developmental history\, function\, and its flexibility to
  change. We use zebrafish as a model system to explore the limits of cell 
 fate specification. By combining scalable single cell RNA-sequencing metho
 ds\, lineage tracing\, and genetic tools\, we aim to study these complex d
 evelopmental processes at multiple scales (molecular\, cellular\, organism
 al). We leverage single-animal barcoding strategies to enable quantificati
 on of molecular and cellular phenotypes in whole developing embryos\, with
  the ultimate goal of understanding how animals overcome genetic and envir
 onmental perturbations and how this underlies morphological evolution.
LOCATION:Part II room\, Department of Genetics and Zoom
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