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SUMMARY:Creating a High-Resolution Meiotic Recombination Map in Arabidopsi
 s - Natasha Elina
DTSTART:20100219T130000Z
DTEND:20100219T133000Z
UID:TALK23074@talks.cam.ac.uk
CONTACT:15560
DESCRIPTION:Meiosis is a reductive cell division resulting in haploid game
 tes necessary for sexual reproduction. Early in meiosis homologous chromos
 omes pair and exchange genetic information\, i.e. undergo recombination\, 
 or crossover. The distribution of crossovers along chromosomes varies in d
 ifferent species and individuals. Although the mechanism of recombination 
 is quite well described in many organisms\, little is known about why some
  regions on the chromosome undergo recombination more frequently than othe
 rs creating the so-called 'hot' and 'cold' spots of recombination. To addr
 ess this question we are creating a high-resolution recombination map of A
 rabidopsis thaliana using restriction-site associated DNA (RAD) sequencing
  combined with Illumina. In parallel we are testing the hypothesis whether
  epigenetic information\, for example\, DNA methylation\, affects the dist
 ribution of 'hot' and 'cold' spots of recombination.\n
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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