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SUMMARY:Neurotransmitter receptor gradients enable flexible control of cor
 tex-wide network dynamics during cognition - Dr Seán Froudist-Walsh
DTSTART:20250612T140000Z
DTEND:20250612T150000Z
UID:TALK233407@talks.cam.ac.uk
CONTACT:Sarah Morgan
DESCRIPTION:Recent advances in neuroanatomy and physiology make it possibl
 e to probe whole-brain mechanisms of cognition and behavior. However\, as 
 yet\, few models in computational neuroscience have tackled the mechanisms
  underlying highly distributed neural activity during cognitive tasks. In 
 this talk I will describe our anatomy-led approach to developing multiscal
 e connectome-based models of neural dynamics during cognitive tasks and ou
 r recent anatomical findings of gradients of neurotransmitter receptors in
  the cortex.  I will highlight our investigations into how inputs from ne
 uromodulatory systems (e.g. dopamine\, serotonin) may dynamically alter th
 e connectome\, shifting the cortical dynamical landscape\, and how this ca
 n confer flexibility on distributed cognitive functions such as conscious 
 perception and working memory.
LOCATION:Online
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