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SUMMARY:A stochastic model of coupled enzymatic degradation - Williams\, R
  (UC\, San Diego)
DTSTART:20100324T093000Z
DTEND:20100324T103000Z
UID:TALK23836@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:Joint work with Natalie Cookson\, Jeff Hasty\, Will Mather\, O
 ctavio Mondragon-Palomino and Lev Tsimring\n\nA major challenge for system
 s biology is to deduce the molecular interactions that underly correlation
 s observed between concentrations of different intracellular molecules.  W
 hile direct explanations such as coupled transcription/translation or dire
 ct protein-protein interactions are often considered\, potential indirect 
 sources of coupling have received much less attention. In this talk\, I wi
 ll report on an investigation involving both theory and experiment of how 
 correlations can arise generically from a post-translational coupling mech
 anism involving the processing of multiple protein species by a common enz
 yme.\n
LOCATION:Seminar Room 1\, Newton Institute
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