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SUMMARY:Functional Genomics in the Opportunistic Pathogen Pseudomonas aeru
 ginosa - Prof Susanne Häußler\, Head of Department of Molecular Bacterio
 logy\, Helmholtz Centre for Infection Research
DTSTART:20260326T160000Z
DTEND:20260326T170000Z
UID:TALK239863@talks.cam.ac.uk
CONTACT:Liat Churley
DESCRIPTION:This Cambridge Immunology Network Seminar will take place on *
 Thursday 26th March 2026*\, starting at *4:00pm*\, in the Ground Floor Lec
 ture Theatre\, Jeffrey Cheah Biomedical Centre (JCBC)\n\n*Speaker*: Profes
 sor Susanne Häußler\, Head of Department of Molecular Bacteriology\, Hel
 mholtz Centre for Infection Research\n\n*Title*: Functional Genomics in th
 e Opportunistic Pathogen Pseudomonas aeruginosa\n\n*Abstract*: The opportu
 nistic pathogen Pseudomonas aeruginosa is a frequent cause of healthcare-a
 ssociated infections and is well known for its remarkable ability to adapt
  to diverse environments. Our research explores how genomic variation cont
 ributes to this adaptability using a range of functional genomics approach
 es.\nBy applying large-scale whole-genome sequencing to clinical isolates\
 , we investigate the population structure and transmission dynamics of P. 
 aeruginosa in hospital settings and explore how bacterial lineages spread 
 and evolve in clinical environments. We further study genotype–phenotype
  relationships related to antibiotic resistance and host adaptation\, as w
 ell as regulatory mechanisms shaping bacterial physiology\, including tran
 scriptional signatures of clinical isolates and post-transcriptional regul
 ation involving transfer RNAs (tRNAs).\nTogether\, these approaches aim to
  shed light on the molecular mechanisms that enable this versatile pathoge
 n to persist and evolve in clinical settings.\n\n\n*Host*: Aaron Weimann\,
  VPD Heart and Lung Research Institute\, Cambridge (on behalf of Professor
  Andres Floto)\n\nRefreshments will be available following the seminar.
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
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