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SUMMARY:Photonic and microfluidic approaches for bioanalytical application
 s - Dr Tracy Melvin\, University of Southampton
DTSTART:20100618T130000Z
DTEND:20100618T140000Z
UID:TALK24978@talks.cam.ac.uk
CONTACT:spl37
DESCRIPTION:Optical tweezers have been applied for trapping mammalian euka
 ryotic\ncells for a number of decades and study continues to be important 
 for\nemerging bioanalytical applications.  Despite this long history\, the
 re\nis a lack of evidence about the trapping and the orientation of\nmamma
 lian eukaryotic cells.  Evidence that eukaryotic cells can be\nstably trap
 ped in a focused Gaussian beam with an orientation that is\ndefined by the
  nucleus will be described.  Our theoretical model allows\ncalculation of 
 the instantaneous trapping force experienced by the cell\nas it moves into
  the Gaussian beam and fits the experimental data.\n\nIn addition to these
  studies\, my group have been developing\nmicrofluidic-optical methods for
  (i) the quantification of low copy\nnumbers of cytokines and (ii) the thr
 eading of long genomic DNA strands\nthrough channels for analysis.  Some o
 f these on-going studies will be\ndiscussed.\n
LOCATION:Kapitza Building Seminar Room\, Cavendish Laboratory\, Department
  of Physics
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