BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Repeat Proteins:Versatile frameworks for understanding and enginee
 ring protein structure and function - Lynne Regan\, Yale University
DTSTART:20110321T161500Z
DTEND:20110321T180000Z
UID:TALK30072@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Repeat proteins\, such as TPR\, ANK\, LRR are prevalent in all
  organisms. Typically\, their function is to mediate protein-protein inter
 actions and to facilitate the assembly of multi-protein complexes. The sim
 ple\, modular architecture of such proteins makes them ideal systems in wh
 ich to investigate fundamental issues of protein stability and folding. Fo
 r the same reasons\, they are well suited to be used as frameworks for the
  design of novel proteins. I will present the results of our work on TPR p
 roteins\, including both fundamental studies of the structure and stabilit
 y of this class of proteins\, and the differences between them and globula
 r protein\, and the design of new TPR modules with a host of novel activit
 ies and applications.
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
END:VEVENT
END:VCALENDAR