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SUMMARY:Marchantia polymorpha: A model for developmental biology and a no
 vel chassis for synthetic biology - Nuri Purswani
DTSTART:20110519T153000Z
DTEND:20110519T160000Z
UID:TALK30685@talks.cam.ac.uk
CONTACT:Suzy Stoodley
DESCRIPTION:Synthetic Biology of eukaryotic systems is highly challenging 
 and there are very few established standards for their manipulation. Liver
 worts are descendants of the most ancient terrestrial plants. In particula
 r\, the Liverwort Marchantia polymorpha (Marchantia) is a promising system
  for developmental biology \, a chassis for synthetic biology and also a
  test bed for reverse engineering plant morphogenesis. This is due to its 
 genetic simplicity with respect to higher plants (haploid\, low genetic re
 dundancy)\; ease of culture and transformation\; modular growth phases and
  optimal size for microscopy. This project provides a description of the 
 early stages of development of this plant through optical microscopy and 3
 D reconstruction techniques. Mapping the developmental stages of Marchant
 ia is the first step towards constructing a standardised framework for ma
 nipulation of the system. The presented results include optimised techniqu
 es for 3D imaging and segmentation of Marchantia cells. A microscopy map
  of Marchantia development will feed directly into a dynamical model of 
 plant morphogenesis and help identify potential genetic markers for engine
 ering the system
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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