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SUMMARY:Molecular studies of meiotic recombination in Arabidopsis thaliana
  and Triticum aestivum - Carsten Reinhard
DTSTART:20110609T150000Z
DTEND:20110609T153000Z
UID:TALK30696@talks.cam.ac.uk
CONTACT:Suzy Stoodley
DESCRIPTION:Meiotic recombination generates gametes with novel combination
 s of genetic information. The distribution of crossover events is not rand
 om along chromosomes\, but the mechanisms controlling their distribution a
 re as yet poorly understood. The overall ambition of my Ph.D. is to study 
 the mechanisms that control crossover frequency at a molecular level\, tak
 ing a comparative approach between Arabidopsis thaliana and Triticum aesti
 vum. Specifically\, my aims are the genomic profiling of purified A. thali
 ana male meiocytes to correlate the patterns of meiotic transcription with
  crossover frequency\, an investigation into the potential effects of the 
 A. thaliana histone chaperone CHROMATIN ASSEMBLY FACTOR-1 on recombination
  frequency\, the characterisation of T. aestivum METHYLTRANSFERASE-1 RNAi 
 lines\, and detailed crossover frequency mapping in A. thaliana and T.aest
 ivum. In the long term\, the data should provide crucial insights into the
  regulation of meiotic recombination of great importance in agricultural b
 reeding.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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