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SUMMARY:Collective migration of neural crest cells: a balance of repulsion
  and attraction - Professor Roberto Mayor\, University College London\, UK
DTSTART:20110920T150000Z
DTEND:20110920T152500Z
UID:TALK31866@talks.cam.ac.uk
CONTACT:Duncan Simpson
DESCRIPTION:The neural crest is a highly migratory embryonic cell populati
 on that gives rise to a huge variety of cells\, tissues and organs. A comp
 lex network of transcription factors and signaling molecules has been invo
 lved in controlling directional migration of neural crest cells.  Our aim 
 is to describe this apparently complex cell behavior based on simple cellu
 lar rules.  We propose that two cellular interactions are sufficient to ge
 nerate directional migration of neural crest: attraction and repulsion bet
 ween cells. I will describe the molecular bases of these repulsive and att
 ractive cellular forces and I will discuss a mathematical model that integ
 rates these different kinds of cell interactions to explain the directiona
 l collective migration of neural crest cells.\n\nhttp://www.ucl.ac.uk/cdb/
 research/mayor
LOCATION:MR2\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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