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SUMMARY:Integrative analysis if environmental sequences - Huson\, D (Unive
 rsity of Tubingen)
DTSTART:20110623T130000Z
DTEND:20110623T140000Z
UID:TALK31907@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:In metagenomics\, the aim is to understand the composition and
  operation of complex microbial assemblages in environmental samples throu
 gh sequencing and analysis of their DNA. Similarly\, metatranscriptomics a
 nd metaproteomics target the RNA and proteins obtained from such samples. 
 A major challenge in the analysis of environmental sequences is data integ
 ration. The question is how to anaylze different types of data in a unifie
 d approach\, addressing both taxonomic and functional aspects. We will dis
 cuss how to perform taxonomic analysis based on the NCBI taxonomy. Functio
 nal analysis can be based on classifications such as the SEED classificati
 on of functional roles and subsystems or the KEGG classification of pathwa
 ys and enzymes. We will also discuss how to compare different datasets usi
 ng statistical approaches\, ecological indices and methods such as Neighbo
 r-net and multi-dimensional scaling. \n
LOCATION:Seminar Room 1\, Newton Institute
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