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SUMMARY:“Genetic analysis of a somatically acquired trait: immunological
  self-tolerance ” - Professor Chris Goodnow is Professor and Head of the
  Dept of Immunology at the Australian National University’s John Curtin 
 School of Medical Research
DTSTART:20120904T160000Z
DTEND:20120904T170000Z
UID:TALK39020@talks.cam.ac.uk
CONTACT:Sylvie Robinson
DESCRIPTION:Professor Chris Goodnow is Professor and Head of the Dept of I
 mmunology at the Australian National University’s John Curtin School of 
 Medical Research\, and Founding Director and CSO of the Australian Phenomi
 cs Facility in Canberra. In May 2009 he was elected as a Fellow of the The
  Royal Society.\nGoodnow “has pioneered in the field of immunology to re
 veal key mechanisms regulating the immune system\, in particular the abili
 ty of the immune system to learn to differentiate between our own “self
 ” tissues and invading foreign microbes. He has also revealed the capaci
 ty of the immune system to lay down specific memory of both self and forei
 gn\, so that autoimmunity is minimised while immunity to infection becomes
  strong”.  \nIn this lecture he will present unpublished work analysing 
 the acquisition of self-nonself discrimination by antibodies during germin
 al center reactions\, and the impact of inherited and somatically acquired
  mutations in genes that are critical for B and T cell tolerance.\n
LOCATION:CRUK Cambridge Research Institute - LiKa Shing Centre - Robinson 
 Way - Cambridge - CB2 0RE
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