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SUMMARY:A genomic Odyssey of predicting drug response: is Ulysses home yet
 ? - Dr Federico Innocenti\, UNC Institute for Pharmacogenomics and Individ
 ualized Therapy
DTSTART:20121106T160000Z
DTEND:20121106T170000Z
UID:TALK39915@talks.cam.ac.uk
CONTACT:Mala Jayasundera
DESCRIPTION:Genomic explorations into the heritable genetic basis of the i
 nterindividual differences in drug response have recently started.  The mo
 st comprehensive approach utilized so far has been the application of geno
 me-wide association studies (GWAS) to patients phenotyped with a variety o
 f clinical endpoints. Using oncology as the case model\, this presentation
  will describe 1) the current status of GWAS in oncology\, with a focus on
  heritable markers\, 2) the journey of finding associations that have a pl
 ausible biological and mechanistic basis\, 3) the clinical implications of
  improving therapies in oncology by using heritable genetic information.
LOCATION:CRI Lecture Theatre
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