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SUMMARY:Recovery and purification of biosynthetic products: Downstream pro
 cessing for the 21st century  -  Dr Graziella El Khoury\, University of Ca
 mbridge\, UK
DTSTART:20131127T090000Z
DTEND:20131127T170000Z
UID:TALK46092@talks.cam.ac.uk
CONTACT:Speaker to be confirmed
DESCRIPTION:The growing interest in biotechnology development and the high
  demand for biopharmaceuticals have contributed to the growth of the globa
 l biopharmaceutical market\, which now comprises over 200 prodcuts. This m
 arket has reached $106 billion in 2009 and is forecasted to grow with a CA
 GR of 11.2% by 2016.                         \n\nThe main challenges of th
 e biopharmaceutical industry now are to increase the efficiency and reduce
  the costs of the manufacturing process\, with respect to the protein reco
 very\, purity and efficacy. Therefore\, new strategies are being implement
 ed for the upstream and downstream processing. In the upstream\, genetic e
 ngineering and glycoengineering approaches\, as well as single-use bioreac
 tors are being developed and applied. However\, as culture yields are cont
 inuously increasing\, the bottleneck in the manufacturing process has shif
 ted to the dowstream processing\, which accounts for ~ 80% of the total pr
 oduction cost. Many aspects are being considered for improving economics i
 n downstream processing\, such as simplification of the chromatographic pu
 rification processes\, application of membrane technology\, crystallizatio
 n and precipitation. \n\nThis meeting will focus on the advances\, innovat
 ion and challenges in the area of downstream processing of biopharmaceutic
 als.\n\nwww.regonline.co.uk/down2013
LOCATION:Cineworld: The O2\, Peninsula Square\, London\, SE10 0DX
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