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SUMMARY:Likelihood Maximization on Phylogenic Trees - Hauser\, R (Universi
 ty of Oxford)
DTSTART:20130719T090000Z
DTEND:20130719T093000Z
UID:TALK46298@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:The problem of inferring the phylogenic tree of $n$ extant spe
 cies from their genome \nis treated via mainly two approaches\, the maximu
 m parsimony and the maximum likelihood approach. While the latter is thoug
 ht to produce more meaningful results\, it is harder to solve computationa
 lly. We show that under a molecular clock assumption\, the maximum likelih
 ood model has a natural formulation that can be approached via branch-and-
 bound and polynomial optimization. Using this approach\, we produce a coun
 terexample to a conjecture relating to the reconstruction of an ancestral 
 genome under the maximum parsimony and maximum likelihood approaches.\n\n
LOCATION:Seminar Room 1\, Newton Institute
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