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SUMMARY:Watching Single Molecules - Professor David Klenerman
DTSTART:20131115T200000Z
DTEND:20131115T210000Z
UID:TALK48027@talks.cam.ac.uk
CONTACT:Ivan Lam
DESCRIPTION:New physical methods have the potential to reveal details of b
 iological and cellular processes that are undetectable using conventional 
 ensemble measurements. I will firstly introduce scanning ion conductance m
 icroscopy\, which allows nanoscale imaging of live cells and controlled de
 livery of molecules to the cell surface. Next I will show how we have deve
 loped single molecule fluorescence to detect the interaction of molecules 
 in the test-tube and on cells. Our recent protein aggregates in neurodegen
 erative disease and the molecular basis of T-cell triggering will be used 
 to show how these methods can provide new biological insights. Lastly I wi
 ll show how such physical methods can lead to new and powerful technologie
 s by describing the development of Solexa next generation DNA sequencing.\
 n\n*Entry is free to all and free refreshments will be provided.*
LOCATION:Pfizer Lecture Theatre\, Department of Chemistry
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